Side Effects of Cloves: What Science Says
- Herbs around us
- Sep 26
- 3 min read
Updated: Nov 7
Introduction
Cloves (Syzygium aromaticum) are known for their rich aroma and long history in cooking, traditional remedies, and even dentistry. Packed with antioxidants, especially eugenol, they offer many potential health benefits.
But like many herbs and spices, cloves are not risk-free. In large amounts or concentrated forms, they can cause side effects and interact with medications. This article examines the potential side effects of cloves, guiding how to use them safely and effectively.

Common Side Effects of Cloves
Mouth and throat irritation
Chewing whole cloves or using clove oil directly on the gums can sometimes cause irritation, burning, or numbness. Dentists occasionally use diluted clove oil for toothaches, but overuse can damage sensitive oral tissues.
Stomach upset
Consuming too many cloves may lead to nausea, bloating, or indigestion. Concentrated clove tea or clove supplements can be especially harsh on sensitive stomachs.
Allergic reactions
Although rare, some people may experience skin rashes or irritation when exposed to clove oil. Performing a patch test before topical use is recommended.
Risks of Clove Oil
High concentration of eugenol
Clove oil is much stronger than the spice itself. In high doses, eugenol can damage the liver and irritate mucous membranes.
Potential toxicity
Reports in medical literature have linked excessive clove oil ingestion to serious complications, including seizures and liver failure. Children are especially vulnerable.
Safety tip
Clove oil should never be ingested in pure form and should always be diluted if applied topically.
Blood-Thinning Effects
Interaction with medications
Eugenol in cloves may act as a natural blood thinner. While this can be beneficial in small amounts, it may increase bleeding risk when combined with medications like warfarin, aspirin, or other anticoagulants.
Surgical concerns
Doctors often advise avoiding clove oil or supplements before surgery, as they may increase the risk of excessive bleeding.
Effects on Blood Sugar
Helpful but risky in excess
Clove extracts may improve insulin sensitivity, which can be beneficial for people managing blood sugar. However, when combined with diabetes medication, it may lower blood sugar too much (hypoglycemia).
Safety recommendation
If you’re on diabetes medication, monitor your levels closely and consult your doctor before adding concentrated clove products.
Special Considerations for Pregnancy and Children
Pregnancy
Culinary use of cloves is safe during pregnancy, but clove oil or supplements should be avoided. Concentrated forms may stimulate uterine contractions or cause toxicity.
Children
Children are more sensitive to clove oil toxicity. Accidental ingestion of even small amounts has been linked to liver and neurological issues. Keep clove oil out of reach.
How to Use Cloves Safely
Stick to culinary amounts: Adding cloves to food or tea in small amounts is safe for most adults.
Avoid swallowing clove oil: Only use diluted oil topically, and under professional guidance.
Check for interactions: If you take blood thinners, diabetes medication, or plan surgery, consult a doctor first.
Introduce gradually: Start with small amounts to monitor tolerance, especially if you’ve never used cloves regularly.
Frequently Asked Questions
1. Can cloves damage the liver?
High doses of clove oil or eugenol may stress the liver. Culinary amounts are considered safe.
2. Is clove tea safe every day?
Yes, in moderation. One cup made with 2–3 cloves is safe for most healthy adults.
3. Are cloves safe for children?
Culinary use in food is fine, but clove oil should never be given to children due to the risk of toxicity.
4. Can cloves cause allergic reactions?
Rarely, yes. Some people may experience skin irritation or rashes when using clove oil topically.
Conclusion
Cloves are a powerful spice with well-documented health benefits; however, science also indicates that concentrated or excessive use can lead to side effects. From stomach irritation and allergic reactions to interactions with medications, it’s important to use cloves wisely.
Enjoy cloves in your cooking or as a mild tea, but be cautious with oils and supplements. When used in moderation, cloves can remain a flavorful and beneficial part of a balanced lifestyle.
References
U.S. Food and Drug Administration. “Generally Recognized as Safe (GRAS).” Updated 2023.
Mayo Clinic. “Clove Oil: Safety and Uses.” 2022.
National Institutes of Health. “Eugenol and Potential Liver Toxicity.” 2020.
Harvard Health Publishing. “Spices and Their Side Effects.” 2023.
Journal of Ethnopharmacology. “Clove Use in Traditional and Modern Medicine.” 2021.